• experimental
  
• epidemiological
  

Do you want to comment on the article?

Submit feedback

Medical/biological Study (experimental study)

Cytogenetic damage in mobile phone users: preliminary data. med./biol.

full article

Journal web site

Aim of study (according to author)
To detect any cytogenetic damage in mobile phone users by analysing lymphocytes cultures for chromosomal aberrations and the buccal mucosal cells for micronuclei.
Background/further details:
Chromosome aberrations were studied in blood lymphocytes of 15 volunteers and micronuclei analysis in buccal cell smear preparations was performed with 25 volunteers. Samples of 25 normal healthy volunteers (who had never used mobile phones) served as controls.

Endpoint

• genotoxicity/mutation: DNA damage (chromosome aberration and micronuclei formation)

Exposure
General category: mobile phone

Field characteristics	Parameters
frequency not specified exposure duration: 2.16 hr/day - 16 hr/day for up to 5 years	SAR: 0.1 W/kg min value SAR: 1.92 W/kg max value

Exposed system:
human
whole body exposure
partial body exposure: head

Methods
Endpoint/Measurement parameters/Methodology

• genotoxicity/mutation: DNA damage (chromosome aberration and micronuclei formation)

Main outcome of study (according to author)
The data showed increased number of micronucleated buccal mucosal cells and cytological abnormalities in cultured lymphocytes indicating the genotoxic response from mobile phone use.

(Study character: medical/biological study, experimental study, pilot/exploratory/preliminary study, blind study)

Study funded by

• not stated

• Hintzsche H et al. (2010): Micronucleus frequency in buccal mucosa cells of mobile phone users.
• Yadav AS et al. (2008): Increased frequency of micronucleated exfoliated cells among humans exposed in...
• Vijayalaxmi et al. (2008): Genetic damage in mammalian somatic cells exposed to radiofrequency radiation:...
• Maes A et al. (2006): Cytogenetic investigation of subjects professionally exposed to radiofrequency...
• Gandhi G et al. (2005): Genetic damage in mobile phone users: some preliminary findings.
• Gadhia PK et al. (2003): A Preliminary Study to Assess Possible Chromosomal Damage Among Users of...
• McNamee JP et al. (2003): No evidence for genotoxic effects from 24 h exposure of human leukocytes to 1.9...
• Mashevich M et al. (2003): Exposure of human peripheral blood lymphocytes to electromagnetic fields...
• Zeni O et al. (2003): Lack of genotoxic effects (micronucleus induction) in human lymphocytes exposed...
• Maes A et al. (2001): Cytogenetic effects of 900 MHz (GSM) microwaves on human lymphocytes.
• Garaj-Vrhovac V (1999): Micronucleus assay and lymphocyte mitotic activity in risk assessment of...
• Maes A et al. (1995): Cytogenetic Effects of Microwaves from Mobile Communication Frequencies (954...
• Garaj-Vrhovac V et al. (1992): The correlation between the frequency of micronuclei and specific chromosome...