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Medical/biological Study (experimental study)Effects of GSM-like radiofrequency on distortion product otoacoustic emissions in pregnant adult rabbits. med./biol. By: Budak GG, Muluk NB, Ozturk GG, Budak B, Apan A, Seyhan N, Sanli C
Published in: Clin Invest Med 2009; 32 (2): E112 - E116 (  PubMed Entry )Aim of study (according to author)
To study the effects of 1800 MHz GSM-like radiofrequency exposure on the cochlear functions of pregnant adult rabbits.
Background/further details:
18 pregnant (day 15-22 of gestation) and 18 non-pregnant rabbits were divided into four groups: 1) Nine pregnant not exposed animals, 2) nine pregnant exposed rabbits, 3) nine non-pregnant not-exposed rabbits, and 4) nine non-pregnant exposed animals. Endpoint - effects on auditory system: effects on cochlear functions
Exposure
General category: digital mobile phone, GSM, PW (pulsed wave) | Field characteristics | Parameters |
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1800 MHz 
pulsed (PW)
exposure duration: continuous for 15 min/day on 7 days | power: 0.1 W
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FIELD View further expo parametersExposed system:
animal (species/strain): rabbit/New Zealand
whole body exposure Methods
Endpoint/Measurement parameters/Methodology - effects on auditory system: effects on cochlear functions (distortion product otoacoustic emissions (DPOAE), mean stimulus intensity and emission amplitudes for the frequencies of 1, 1.5, 2, 3, 4, 6 and 8 Hz); ear examination (otoscope)
investigation on living organism
investigated organ system: sense organs, ear
time of investigation: before and after exposure
Main outcome of study (according to author)
DPOAE amplitudes were not different for exposed and not exposed pregnant animals except for 2.0 kHz (decreased in exposed animals). In group 4 (non-pregnant, exposed), DPOAE amplitudes at 1.0-4.0 kHz were lower than in group 3 (non-pregnant, not exposed rabbits). In the pregnant group, harmful effects of GSM-like radiofrequency exposure were less present than in the non-pregnant group. During pregnancy increased inner ear volume may help to reduce the damage.
The authors conclude that GSM-like radiofrequency exposure caused decreases in DPOAE amplitudes mainly in non-pregnant adult rabbits. Prolonged exposure may affect the DPOAE amplitude. (Study character: medical/biological study, experimental study, full/main study)
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Glossary: adult, amplitude, animals, auditory, biological, cochlear, digital, DPOAE, ear, emission, endpoint, exposed, exposure, frequencies, full/main study, gestation, GSM, Hz, inner ear, kHz, mean, MHz, mobile phone, power, pregnant, pulsed, PW, radiofrequency, sense organs, species, stimulus, strain, whole body exposure |
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