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Medical/biological Study (experimental study)

Effects of 2.45 GHz microwave exposures on the peroxidation status in Wistar rats. med./biol.

By: Aweda MA, Gbenebitse S, Meidinyo RO
Published in: Niger Postgrad Med J 2003; 10 (4): 243 - 246 ( open external web page PubMed Entry , open external web page Journal web site )

Aim of study (according to author)
To study the effect of microwave exposure on lipid peroxidation status in rats.
Background/further details:
The effect of administration of the antioxidants ascorbic acid and alpha-tocopherol was also studied.
120 rats were divided into the following groups (each group = 5 rats): Six groups served as control group, six groups were microwave exposed, six groups were treated with ascorbic acid, and six groups were treated with alpha-tocopherol (both four days before exposure). The lipid peroxidation was monitored for a period of 8 weeks post irradiation.

Endpoint

Exposure
General category: microwaves, 2.45 GHz

Field characteristicsParameters
2.45 GHz
exposure duration: not given in the article		power flux density: 6 mW/cm² max value

FIELD View further expo parameters

Exposed system:
animal (species/strain): rat/Wistar
whole body exposure

Methods
Endpoint/Measurement parameters/Methodology

investigated material: blood samples
investigation on living organism

time of investigation: during and after exposure

Main outcome of study (according to author)
The microwave exposure caused an increase in the lipid peroxidation within the first 24 hours after exposure, and then gradually reduced to the value of the control group after about one week. Ascorbic acid and alpha-tocopherol administration caused a decrease of the control value of the lipid peroxidation within the first week after irradiation.
The data demonstrated that microwave exposure caused significant increase in the lipid peroxidation status and there were protective effects of the antioxidants ascorbic acid and alpha-tocopherol.

(Study character: medical/biological study, experimental study, full/main study)

Study funded by

  • not stated

Related articles i
Glossary: alpha-tocopherol, animal, antioxidants, ascorbic acid, biological, blood, control group, endpoint, exposed, exposure, full/main study, GHz, irradiation, lipid peroxidation, malondialdehyde, microwave, plasma, power flux density, rat/Wistar, rats, rectal temperature, SAR, significant, species, spectrophotometry, strain, thiobarbituric acid, whole body exposure

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