Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
Age of exposure to infections and risk of childhood leukaemia.
epidem.
[Alter bei Exposition gegenüber Infektionen und das Risiko für Kinderleukämie].
Von:
Petridou E, Kassimos D, Kalmanti M, Kosmidis H, Haidas S, Flytzani V, Tong D, Trichopoulos D
Veröffentlicht in: BMJ 1993; 307 (6907): 774
Ziel der Studie (lt. Autor)
Endpunkt/Art der Risikoabschätzung
Exposition
Abschätzung
Expositionsgruppen
|
Gruppe
|
Charakteristik
|
|
Referenzgruppe 1
|
Abstand zu Hochspannungsfreileitungen: ≥ 50 m
|
|
Gruppe 2
|
Abstand zu Hochspannungsfreileitungen: 5 - 49 m
|
|
Gruppe 3
|
Abstand zu Hochspannungsfreileitungen: < 5 m
|
|
Referenzgruppe 4
|
Abstand zur Umspannstation: ≥ 100 m
|
|
Gruppe 5
|
Abstand zur Umspannstation: < 100 m
|
Population
-
Gruppe:
-
Alter:
0–14 Jahre
-
Beobachtungszeitraum:
Juli 1987 - Juni 1991
-
Studienort:
Griechenland (Athen und Umgebung, Kreta)
Fallgruppe
-
Merkmale:
Kinderleukämie
-
Datenquelle:
Kinderkrankenhäuser der Universitäten Athen und Kreta, Griechenland
Kontrollgruppe
Studiengröße
|
Fälle |
Kontrollen |
| Anzahl geeignet |
183 |
- |
| Teilnehmerzahl |
136 |
187 |
Statistische Analysemethode:
- multiple lineare Regressionsanalyse
Schlussfolgerung (lt. Autor)
Die Ergebnisse zu den beiden Feldquellen von Magnetfeldern lassen entgegensetzte Schlussfolgerungen zu. Kinder, die in einem Abstand von weniger als 100 m von einer elektrischen Umspannstation entfernt lebten, hatten ein nicht-signifikant verringertes Risiko für Kinderleukämie (RR 0,35; KI 0,12-1,08). Dahingegen wiesen Kinder, die weniger als 5 m von Hochspannungsfreileitungen lebten, einen leichten, aber nicht signifikanten Anstieg des relativen Risikos für Kinderleukämie auf (RR 1,19; KI 0,59-2,41).
Studie gefördert durch
-
Ministry of Health, Greece
-
University of Harvard, USA
Themenverwandte Artikel
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Residential magnetic fields exposure and childhood leukemia: a population-based case-control study in California.
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Childhood leukaemia and distance from power lines in California: a population-based case-control study.
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Epidemiological study of power lines and childhood cancer in the UK: further analyses.
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Childhood Leukemia and 50 Hz Magnetic Fields: Findings from the Italian SETIL Case-Control Study.
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Increased risk of childhood acute lymphoblastic leukemia (ALL) by prenatal and postnatal exposure to high voltage power lines: a case control study in Isfahan, Iran.
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Role of electromagnetic field exposure in childhood acute lymphoblastic leukemia and no impact of urinary alpha-amylase - a case control study in Tehran, Iran.
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