Studientyp:
Epidemiologische Studie
Proximity to overhead power lines and childhood leukaemia: an international pooled analysis
epidem.
[Wohnnähe zu Hochspannungsfreileitungen und Kinderleukämie: eine internationale gepoolte Analyse]
Von:
Amoon AT, Crespi CM, Ahlbom A, Bhatnagar M, Bray I, Bunch KJ, Clavel J, Feychting M, Hémon D, Johansen C, Kreis C, Malagoli C, Marquant F, Pedersen C, Raaschou-Nielsen O, Röösli M, Spycher BD, Sudan M, Swanson J, Tittarelli A, Tuck DM, Tynes T, Vergara X, Vinceti M, Wünsch-Filho V, Kheifets L
Veröffentlicht in: Br J Cancer 2018; 119 (3): 364-373
Ziel der Studie (lt. Autor)
Weitere Details
Endpunkt/Art der Risikoabschätzung
Art der Abschätzung:
(Odds Ratio (OR))
Exposition
Abschätzung
Expositionsgruppen
Gruppe
|
Charakteristik
|
Referenzgruppe 1
|
Abstand zu Hochspannungsfreileitung: ≥ 300 m
|
Gruppe 2
|
Abstand zu Hochspannungsfreileitung: 150 - < 300 m
|
Gruppe 3
|
Abstand zu Hochspannungsfreileitung: 50 - < 150 m
|
Gruppe 4
|
Abstand zu Hochspannungsfreileitung: < 50 m
|
Referenzgruppe 5
|
Abstand zu ≥ 200 kV Hochspannungsfreileitung: ≥ 300 m
|
Gruppe 6
|
Abstand zu ≥ 200 kV Hochspannungsfreileitung: 150 - < 300 m
|
Gruppe 7
|
Abstand zu ≥ 200 kV Hochspannungsfreileitung: 50 - < 150 m
|
Gruppe 8
|
Abstand zu ≥ 200 kV Hochspannungsfreileitung: < 50 m
|
Population
-
Gruppe:
-
Alter:
0–14 Jahre
-
Beobachtungszeitraum:
1960 - 2014
-
Studienort:
Brasilien, USA, Dänemark, Frankreich, Italien, Norwegen, Schweden, Schweiz, Australien, Großbritannien
Fallgruppe
Kontrollgruppe
Studiengröße
|
Fälle |
Kontrollen |
Gesamtzahl |
30.500 |
69.594 |
Anzahl auswertbar |
27.143 |
65.265 |
Statistische Analysemethode:
(
Anpassung:
- Alter
- Geschlecht
- sozioökonomischer Status
- Mobilität, Wohnungsart, Verkehr, Umgebung (Stadt/Land), berechnete oder gemessene Magnetfelder
)
Ergebnisse (lt. Autor)
Es wurde kein Zusammenhang zwischen Kinderleukämie und der Wohnnähe zur nächstgelegenen Hochspannungsfreileitung unabhängig von der Spannung beobachtet (Gruppe 2-4). Ein nicht-signifikant erhöhtes Risiko wurde bei Kindern beobachtet, die < 50 m zu einer ≥ 200 kV-Hochspannungsfreileitung gewohnt hatten (Gruppe 8: OR 1,33; KI 0,92-1,93), dies war bei Kindern mit einer Diagnose im Alter bis zu 5 Jahren höher. Der Zusammenhang konnte nicht durch die Exposition bei höheren magnetischen Flussdichten (≥ 0,4 µT) oder durch andere Confounder erklärt werden.
Die Autoren schlussfolgerten, dass in dieser ersten umfangreichen gepoolten Analyse zu Kinderleukämie und der Wohnnähe zu Hochspannungsfreileitungen ein kleines, nicht-signifikantes Risiko für Kinder, die < 50 m zu einer ≥ 200 kV-Hochspannungsfreileitung gewohnt hatten, gefunden wurde, dass nicht mit höheren Magnetfeldern erklärt werden konnte. Die Gründe für das erhöhte Risiko, das in dieser und vielen anderen Studien gefunden wurde, müssen noch aufgeklärt werden.
Studie gefördert durch
-
Electric Power Research Institute (EPRI), USA
Themenverwandte Artikel
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(2022):
Pooled analysis of recent studies of magnetic fields and childhood leukemia
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