Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
Exposure to power-frequency magnetic fields and the risk of childhood cancer
epidem.
[Exposition bei magnetischen Netzfrequenz-Feldern und das Risiko für Krebs im Kindesalter]
Von:
UK Childhood Cancer Study Investigators
Veröffentlicht in: Lancet 1999; 354 (9194): 1925-1931
Ziel der Studie (lt. Autor)
Weitere Details
Die Studie ist der EMF-Teil der UK-Kinderkrebs-Studie (UKCCS), in der fünf Hypothesen zu möglichen Ursachen von Kinderkrebs untersucht wurden.
Es wurden Messungen in einer Wohnung durchgeführt, wenn das Kind an der jetzigen Adresse ein Jahr vor Diagnosestellung lebte. In der Publikation 4760 sind weitere Ergebnisse, die auf Berechnungen der Magnetfeld-Exposition beruhen, veröffentlicht.
Endpunkt/Art der Risikoabschätzung
Art der Abschätzung:
(Odds Ratio (OR))
Exposition
Abschätzung
Expositionsgruppen
|
Gruppe
|
Charakteristik
|
|
Referenzgruppe 1
|
arithmetisches Mittel des Magnetfelds: < 0,1 µT
|
|
Gruppe 2
|
arithmetisches Mittel des Magnetfelds: < 0,1 - 0,2 µT
|
|
Gruppe 3
|
arithmetisches Mittel des Magnetfelds: ≥ 0,2 µT
|
|
Gruppe 4
|
arithmetisches Mittel des Magnetfelds: 0,2 - < 0,4 µT
|
|
Gruppe 5
|
arithmetisches Mittel des Magnetfelds: ≥ 0,4 µT
|
Population
-
Gruppe:
-
Alter:
0–14 Jahre
-
Beobachtungszeitraum:
01/1991 - 12/1994 in Schottland, 4/1992 - 12/1994 in Wales und England, 1995 für Leukämie + Non-Hodgkin-Lymphom, 1996 f. Leukämie
-
Studienort:
Großbritannien (England, Schottland und Wales)
Fallgruppe
-
Merkmale:
Krebs
-
Datenquelle:
Gesundheitsbehörden
-
Ausschlusskriterien:
außerhalb der Studienregion geboren, vorangegangene maligne Erkrankung
Kontrollgruppe
Studiengröße
|
Fälle |
Kontrollen |
| Anzahl geeignet |
3.938 |
7.629 |
| Teilnehmerzahl |
2.423 |
2.416 |
| Anzahl auswertbar |
2.226 |
2.226 |
Statistische Analysemethode:
- konditionale logistische Regression
(
Anpassung:
- Alter
- Geschlecht
- Region
- sozioökonomischer Status
)
Ergebnisse (lt. Autor)
Studie gefördert durch
-
Cancer Research Campaign (CRC), UK
-
Children with Leukaemia Foundation, UK
-
Department of Health, UK
-
Electricity Association, UK
-
Electricity Supply Board (ESB), Ireland
-
Imperial Cancer Research Fund (ICRF), UK
-
Kay Kendall Leukaemia Fund (KKLF), UK
-
Leukaemia Research Fund (LRF), UK
-
Medical Research Council, UK
-
National Grid Company plc, UK
-
National Radiological Protection Board (NRPB), UK
-
Scottish Hydro-Electric plc, UK
-
Scottish Nuclear Ltd (SNL), UK
-
Scottish Office, UK
-
ScottishPower plc, UK
-
UK Childhood Cancer Study (UKCCS) paediatric oncologists, UK
-
UK Co-ordinating Committee on Cancer Research (UKCCCR), UK
-
Westlakes Research (Trading) Ltd (WRTL), UK
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