Study type: Medical/biological study (experimental study)

Effect of a 0.5-T static magnetic field on conduction in guinea pig spinal cord med./bio.

By: Coots A, Shi R, Rosen AD
Published in: J Neurol Sci 2004; 222 (1-2): 55-57
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Aim of study (acc. to author)

To investigate the effects of a static magnetic field (SMF) on conduction in guinea pig spinal cord in vitro.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: 5 min

Exposure 1

Main characteristics
Frequency
Type
Exposure duration 5 min
Exposure setup
Exposure source
Setup Spinal cord segments were centered between the poles of the water cooled electromagnet with the magnetic field perpendicular to the long axis of the cord segmets.
Additional info The cords were stimulated twice per second with 150 µs square waves, 9-15 V.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 500 mT unspecified unspecified - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

No change in response latency was observed during exposure. A small, but statistically significant decrease in amplitude was observed with a maximum 1 to 2 min after the start of exposure and turned back to baseline 1 min after exposure. The observed effect might be ascribed to voltage-activated sodium channels.

Study character:

Study funded by