Study type: Medical/biological study (experimental study)

Syrian hamster dermal cell immortalization is not enhanced by power line frequency electromagnetic field exposure. med./bio.

Published in: Br J Cancer 1999; 81 (3): 377-380

Aim of study (acc. to author)

This in vitro study was performed to investigate the effects of electromagnetic fieds on the cell immortalization of hamster dermal cells in the presence or absence of a known carcinogen (gamma radiation, at 0.5 or 1.5 Gy)

Background/further details

Syrian hamster dermal cells were chosen as investigated cell line as they show very low frequency of spontaneous immortalization. Cell immortalization can be a sign of tumor initiation.
The cells were exposed to electromagnetic fields at the levels commonly encountered in the home.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Modulation type: CW
Exposure duration: 60 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 60 h
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber 2 identical insulated chambers with munetal shielding
Setup ten 75 cm² tissue culture flasks in a levelled carrier within solenoid
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 44 µT - cf. remarks - DC superimposed for earth MF
magnetic flux density 1,000 µT maximum measured - -
magnetic flux density 100 µT - measured - -
magnetic flux density 10 µT minimum measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The electromagnetic field exposure alone did not cause cell immortalization in the investigated cell line. Furthermore the electromagnetic fields exposures did not enhance the frequency of ionizing radiation-induced immortalization.

Study character:

Study funded by

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