Eight rats were exposed and eight rats were sham-exposed. A modified comet assay was used to increase the sensitivity and to detect oxidative DNA damage.
This article has been retracted at the request of the Editors-in-Chief (further details).
|Exposure duration||continuous for 1 h/day, 7 days/week for 2 weeks|
Both the standard and the Fpg-modified comet assay detected increased DNA damage in blood leukocytes of the exposed rats. The significant increase in the Fpg-detected DNA damage suggests that oxidative stress is likely to be responsible. DNA damage detected by the standard comet assay indicates that some other mechanisms may also be involved.