Study type: Medical/biological study (experimental study)

Chronic exposure of Sprague-Dawley rats to 20 kHz triangular magnetic fields. med./bio.

Published in: Int J Radiat Biol 2010; 86 (5): 384-389

Aim of study (acc. to author)

This study was conducted to investigate the effects of long-term exposure (18 months) to 20 kHz intermediate frequency magnetic fields on different physiological parameters in rats.

Background/further details

80 rats were divided into four groups (male and female separately, two sham exposed and two exposed groups). The applied magnetic flux density of 30 µT represents the exposure limit value for the occupational exposure of 20 kHz magnetic fields in Korea (in contrast to the applied magnetic flux density of a previous study (Lee et al. 2006) representing the exposure limit for the general population (6.25 µT)).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 20 kHz
Exposure duration: continuous for 8 hr/day, 5 days/week over 18 months

Exposure 1

Main characteristics
Frequency 20 kHz
Type
Exposure duration continuous for 8 hr/day, 5 days/week over 18 months
Additional info triangular waves
Exposure setup
Exposure source
Setup 420 cm x 260 cm x 180 cm polycarbonate cages
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 30 µT effective value measured - at the center of the top panel
magnetic flux density 31.09 µT effective value measured - +/- 1.16 µT at the top panel
magnetic flux density 30.73 µT effective value measured - +/- 0.46 µT at the bottom panel
magnetic flux density 0.11 µT - measured - 60 Hz component

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The data showed that exposure of rats to a 20 kHz intermediate frequency magnetic field with 30 µT flux density for 18 months did not induce any abnormalities in organ weights and did not induce any significant changes in hematological factors, blood biochemistry, urological factors, and histopathological findings. Total tumour incidence was not different between sham-exposed and magnetic field-exposed animals.

Study character:

Study funded by

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