Study type: Epidemiological study (observational study)

Living near overhead high voltage transmission power lines as a risk factor for childhood acute lymphoblastic leukemia: a case-control study epidem.

Published in: Asian Pac J Cancer Prev 2010; 11 (2): 423-427

Aim of study (acc. to author)

A case-control study was conducted in Iran to investigate whether living near power transmission lines is associated with an increased risk of childhood acute lymphoblastic leukemia.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))



Exposure groups

Group Description
Group 1 distance of residence to power line: 0 - 599 m
Group 2 distance of residence to power line: 600 - 1199 m
Group 3 distance of residence to power line: 1200 - 1799 m
Group 4 distance of residence to power line:1800 - 2399 m
Group 5 distance of residence to power line: ≥ 2400 m


Case group

Control group

Study size

Cases Controls
Participants 300 300
Statistical analysis method:

Results (acc. to author)

Children with acute lymphoblastic leukemia were living significantly closer to power lines than the control group (P<0.001). More than half of the cases were exposed to two or three power lines (P<0.02).
A statistically significant increased risk for acute lymphoblastic leukemia was observed in children who were living in a distance of less than 600 m to power lines (OR 2.61, CI 1.73-3.94). Separate analysis for each type of power lines showed an increased risk estimate for 123 kV (OR 9.93, CI 3.47-28.5), for 230 kV (OR 10.78, CI 3.75 to 31), and for 400 kV (OR 2.98, CI 0.93- 9.54).
The authors conclude that the study emphasizes that living close to high voltage power lines is a risk for childhood acute lymphoblastic leukemia.

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