Study type: Medical/biological study (experimental study)

Detection of oxidative stress induced by mobile phone radiation in tissues of mice using 8-oxo-7, 8-dihydro-20-deoxyguanosine as a biomarker. med./bio.

Published in: World Acad Sci Eng Technol 2011; 76: 657-622

Aim of study (acc. to author)

To study the extent of radiofrequency induced oxidative DNA damage by measuring the level of 8-hydroxy-2-deoxyguanosine in mice tissues after 900 MHz mobile phone exposure.

Background/further details

36 mice were divided into an exposure group and a sham exposure group (each group n=18; with three subgroups of six mice each). Tissue samples were taken 24 h after exposure.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: 30 min/day for 30 days
  • SAR: 1 W/kg average over mass (whole body) (equivalent to 25 V/m)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration 30 min/day for 30 days
Exposure setup
Exposure source
Chamber mice placed randomly in groups of six animals in plastic cages exposed to the mobile phone fields
Setup the antenna was located about 5 cm next to the cage
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 1 W/kg average over mass measured and calculated whole body equivalent to 25 V/m

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • before exposure
  • after exposure

Main outcome of study (acc. to author)

All animals survived the whole experimental period and the body weight of the animals did not change significantly at the end of the experiment. Additionally, no statistically significant differences were found in the parameters of oxidative stress.
In conclusion, the data indicate that a 900 MHz radiofrequency exposure did not induce a significant oxidative DNA damage under these experimental conditions.

Study character:

Study funded by

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