Study type: Medical/biological study (experimental study)

The influence of microwave radiation from cellular phone on fetal rat brain med./bio.

Published in: Electromagn Biol Med 2012; 31 (1): 57-66

Aim of study (acc. to author)

To evaluate the intensity of oxidative stress and the level of neurotransmitters in the brains of fetal rats exposed to cellular phones.

Background/further details

Pregnant rats were divided into four groups (n=8 per group): 1.) sham exposed, 2.) 10 minutes exposed, 3.) 30 minutes exposed and 4.) 60 minutes exposed. At the 21th day of pregnancy, rats were sacrificed and 5 foetuses were taken out of the uterus of each rat.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
  • unspecified
Exposure duration: 3 times per day (3 x 10, 30 or 60 min) for 20 days during gestation
  • SAR: 0.9 W/kg

Exposure 1

Main characteristics
Frequency
  • unspecified
Type
Exposure duration 3 times per day (3 x 10, 30 or 60 min) for 20 days during gestation
Exposure setup
Exposure source
Setup 24 cm long iron wire tube cage with a diameter of 7 cm; rat's movement restrained in the cage; during exposure mobile phone's antenna kept close to the rat's ear
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.9 W/kg - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In the 30 and 60 minutes exposed group, the enzyme activities of superoxide dismutase and glutathione peroxidase were significantly decreased while the level of malondialdehyde was increased in comparison to the sham exposed group.
The levels of norepinephrine and dopamine were significantly increased in the 10 minutes group and decreased in the 60 minutes group when compared to the sham exposed group. No changes in the level of 5-hydroxyindoleacetic acid were observed among the groups.

Study character:

Study funded by

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