Deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure. med./bio.

Aim of study (acc. to author)

Background/further details

Endpoint

• effects on the neurological system: oxidative stress in the brain
• cognitive/behavioral endpoints: learning and memory

Exposure

• • 50/60 Hz
  • magnetic field

Extended view Compact view

Methods Endpoint/measurement parameters/methodology

• effects on the neurological system: oxidative stress in the striatum and hippocampus (enzyme activities of catalase and glutathione peroxidase, total antioxidant capacity (spectrophotometry), malondialdehyde level (as marker of lipid peroxidation; via thiobarbituric acid-reactive substances; spectrophotometry))
• cognitive/behavioral endpoints: learning and memory (habit learning and spatial learning; two modified Morris water maze tasks to study two different brain areas (striatum and hippocampus)); locomotor activity (open field test)
• body weight

Main outcome of study (acc. to author)

Study funded by

• Chinese National Science Foundation
• National Basic Research Program (Program 973), China

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