Study type: Medical/biological study (experimental study)

Plasma and red cell volumes of microwave irradiated mice tissues tech./dosim.

By: Virkkunen P
Published in: Acta Physiol Scand 1982; 115 (2): 161-164
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Aim of study (acc. to editor)

To measure the distribution of erythrocytes and blood plasma in various organs of mice. For these purposes erythrocytes were double radioactive labelled extracorporeal (outside the body) and than reinjected into mice. Letal microwave exposure was used to prevent blood flow during organ isolation by coagulation. The results were compared with those obtained by sacrificing animals by decapitation.

Background/further details

Organs studied were: liver, kidney, spleen, intestine, lung, and brain.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: depending on weight of mice

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration depending on weight of mice
Exposure setup
Exposure source
Chamber round glass bowl, 10 cm diameter
Parameters
Measurand Value Type Method Mass Remarks
power 1.3 kW - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The loss of blood caused by decapitation compared to sacrifice with microwave was in the range of 6% (for kidney) to more than 50% (for brain). Therefore the double isotope/microwave method is a valuable technique to determine plasma and erythrocyte values (and within hematocrit).

Study character:

Study funded by