Study type: Medical/biological study (experimental study)

The lack of effects of nonthermal RF electromagnetic fields on the development of rat embryos grown in culture. med./bio.

Published in: Life Sci 1997; 61 (18): 1789-1802

Aim of study (acc. to author)

To study the influence of either an electric field or a magnetic field on rat embryonic development.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 150 MHz
Modulation type: AM
Exposure duration: continuous for 36 h
Exposure 2: 150 MHz
Modulation type: AM
Exposure duration: continuous for 36 h
Exposure 3: 150 MHz
Modulation type: AM
Exposure duration: continuous for 36 h
Exposure 4: 150 MHz
Modulation type: AM
Exposure duration: continuous for 36 h
Exposure 5: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 36 h
Exposure 6: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 36 h

Exposure 1

Main characteristics
Frequency 150 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 36 h
Modulation
Modulation type AM
Modulation frequency 16–60 Hz
Modulation depth 100 %
Additional info

Frequencies of 16 and 60 Hz were used.

Exposure setup
Exposure source
Chamber A rectangular cavity resonator was made from 22 mm plywood coated with 0.5 mm copper plates.
Additional info In two different runs with control samples, the samples were exposed in the EF maximum at half the resonator length or in the MF maximum at zero length.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 60 V/m - measured - -
electric field strength 600 V/m - measured - -

Exposure 2

Main characteristics
Frequency 150 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 36 h
Modulation
Modulation type AM
Modulation frequency 120 Hz
Modulation depth 100 %
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 600 V/m - measured - -

Exposure 3

Main characteristics
Frequency 150 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 36 h
Modulation
Modulation type AM
Modulation frequency 16 Hz
Modulation depth 100 %
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.2 µT - measured - -
magnetic flux density 2 µT - measured - -

Exposure 4

Main characteristics
Frequency 150 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 36 h
Modulation
Modulation type AM
Modulation frequency 60 Hz
Modulation depth 100 %
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 µT - measured - -

Exposure 5

Main characteristics
Frequency 900 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 36 h
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Exposure setup
Exposure source
Chamber A rectangular cavity resonator was made from 22 mm plywood coated with 6 mm aluminium plates and placed into an incubator system.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.2 W/kg - calculated - -
electric field strength 14 V/m - measured - -
SAR 1 W/kg - calculated - -
electric field strength 32 V/m - measured - -
SAR 5 W/kg - calculated - -
electric field strength 71 V/m - measured - -

Exposure 6

Main characteristics
Frequency 900 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 36 h
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Exposure setup
Exposure source
  • same setup as in E5
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.2 W/kg - calculated - -
magnetic flux density 50 nT - measured - -
SAR 1 W/kg - calculated - -
magnetic flux density 110 nT - measured - -
SAR 5 W/kg - calculated - -
magnetic flux density 240 nT - measured - -

Reference articles

  • Dimbylow PJ et al. (1994): SAR calculations in an anatomically realistic model of the head for mobile communication transceivers at 900 MHz and 1.8 GHz.
  • Hetscher M et al. (1992): Generation of homogeneous electric and magnetic fields at radio frequencies in a cavity resonator
  • Saito K et al. (1991): Lethal and teratogenic effects of long-term low-intensity radio frequency radiation at 428 MHz on developing chick embryo.

Methods Endpoint/measurement parameters/methodology

Investigated material:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Neither the electric fields nor the magnetic fields tested interfered significantly with the normal growth and differentiation of the embryos in vitro.

Study character:

Study funded by

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