The study analyzed the optimal treatment regimen of one pulsed electromagnetic field signal on the turnover of both total and [35S]-sulfated glycosaminoglycans and the structure of [35S]-sulfated proteoglycans in embryonic chick sternal cartilage explanted to culture.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
1.5 Hz
Modulation type:
pulsed
Exposure duration:
repeated daily exposure, 3 h/day for 2 days
|
|
| Frequency | 1.5 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | repeated daily exposure, 3 h/day for 2 days |
| Additional info | Reference article: Bee JA, Lin H-X, Abbott J. Pulsed electromagnetic fields influence both proteoglycan synthesis and degradation by developing cartilages explanted to culture (abstract). Trans Orthop Res 1994; 19: 362 |
| Exposure source | |
|---|---|
| Setup | Culture dishes placed between the coils and maintained at 37°C under 5 % CO2. |
| Additional info | Control cultures were maintaiened within the coils under identical enviromental conditions in the absense of pulsed electromagnetic field. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 100 µT | maximum | - | - | during rise time |
The results demonstrated that exposure of embryonic chick cartilage explants to pulsed electromagnetic fields (3h/day) maintains a balanced proteoglycan composition by down-regulation its turnover without affecting either molecular structure or function.
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