Study type: Medical/biological study (experimental study)

Microwaves and the cell membrane. IV. Protein shedding in the human erythrocyte: quantitative analysis by high-performance liquid chromatography med./bio.

By: Liburdy RP, Rowe AW, Vanek Jr PF
Published in: Radiat Res 1988; 114 (3): 500-514
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Aim of study (acc. to author)

To investigate the phenomenon of protein shedding in human erythrocytes caused by mircowave irradiation.

Background/further details

Quantitative and qualitative protein determination was assessed by using different methods of high performance liquid chromatography (HPLC) and erythrocyte blood group antigen testing, respectively.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: continuous for 30 min
-

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration continuous for 30 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters

No parameters are specified for this exposure.

Reference articles

  • Liburdy RP et al. (1985): Microwaves and the cell membrane. II. Temperature, plasma, and oxygen mediate microwave-induced membrane permeability in the erythrocyte

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Microwave exposure leads to an approximate twofold release of protein mass. The released proteins were characterized as hydrophobic, positive net charged, and nonpolar. The results of the blood group antigen testing support the idea that these proteins are loosely peripheral bound to the cell surface.

Study character:

Study funded by