Study type: Medical/biological study (experimental study)

Cytological effects of microwave radiation in Chinese hamster cells in vitro. med./bio.

Published in: Can J Genet Cytol 1978; 20 (1): 23-30

Aim of study (acc. to author)

To investigate cytological effects in Chinese hamster ovary cell line (CHO-K1) in vitro exposed to microwave irradiation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: 30 min

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Exposure duration 30 min
Exposure setup
Exposure source
Setup tissue culture flask
Parameters
Measurand Value Type Method Mass Remarks
power density 200 mW/cm² minimum measured - at the surface of cell medium
power 25 W - cf. remarks - 75 W, 125 W and 200 W

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In cells exposed to 25 W under uncontrolled, increased temperature conditions nuclear vacuoles, pycnotic and decondensed chromosomes were observed. Further on a significant increase in chromosomal breakages per cell was observed. Cells showed no significant increase in neither formation of nuclear vacuoles nor in chromosomal anomalies compared to control cells when exposed to higher power (75-200 W) under controlled hypothermic conditions (29°C) Temperature elevation induced by radiation seems to be an essential factor of microwave caused cytological effects.

Study character:

Study funded by