inositol 1,4,5-triphosphate

Synonyms:
  • IP3
German: Inositol-1,4,5-triphosphat
Japanese: イノシトール1,4,5-三リン酸

Biochemistry. A second messenger involved in the signal transduction system resulting in increase of intracellular calcium. It is formed by the action of the enzyme phospholipase C on the membrane phospholipid phosphatidylinositol 4,5-bisphosphate. It causes the release of calcium ions from intracellular stores thus stimulating the activity of protein kinase C.

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