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Gene expression changes were examined in three experiments and investigation of protein expression changes were replicated in ten experiments.
The work is part of the REFLEX project (Risk Evaluation of Potential Environmental Hazards From Low Energy Electromagnetic Field Exposure Using Sensitive in vitro Methods), funded by the European Union.
Modulation type: pulsed
ばく露時間: continuous for 1 h
|ばく露時間||continuous for 1 h|
|ばく露装置の詳細||Cells were irradiated with a simulated mobile phone microwave radiation as described in [Leszczynski et al., 2002].|
|Sham exposure||A sham exposure was conducted.|
|Additional information||The temperature of the cells and the culture medium remained at 37 ± 0.2°C throughout the exposure period.|
The data showed that gene and protein expression are altered in both cell lines in response to mobile phone irradiation. Furthermore, different genes and different proteins were affected by the same exposure in both cell lines. This suggest that under these experimental conditions the cell responses might be genome- and proteome-dependent.