研究のタイプ: 医学/生物学の研究 (experimental study)

[50Hz電磁界への亜急性ばく露は出生前および新生仔期のマウスの運動協調に影響する] med./bio.

Subacute exposure to 50-Hz electromagnetic fields affect prenatal and neonatal mice's motor coordination

掲載誌: J Appl Phys 2012; 111 (7): 07B314-1-07B314-3

この研究は、マウスを用いた実験で、出生前および新生仔期に超低周波電磁界(ELF-EMF)のばく露を受けたマウスにおいて、運動能力への影響を調べた。マウスを3群に分けた。すなわち、出生後ばく露群(母マウスと共に新生仔マウスを出生後7日間ばく露)、出生前ばく露群(母マウスを妊娠の最後の7日間ばく露)、対照群である。回転ホイールを用いたマウスの運動協調性とバランスの試験は、7日間ばく露終了の5日後から生後12-13週まで実施した。その結果、新生仔期の出生後ばく露群では、対照群に比べ、

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研究目的(著者による)

To investigate the effects of extremely low frequency magnetic fields on the motor coordination of prenatally and neonatally exposed mice.

詳細情報

Mice were divided into three groups (n=7-18 per group): 1.) exposure of dams and offspring for 7 days after birth, 2.) exposure of dams during the last 7 days of pregnancy and 3.) control group. Motor coordination experiments were performed with the offspring in the age of 12 to 13 weeks.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 50 Hz
ばく露時間: continuous for 7 days

ばく露1

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
波形
  • sinusoidal
ばく露時間 continuous for 7 days
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 each of the coils was 40 cm in diameter, had 154 turns, and the coils were separated at a distance of 20 cm
Sham exposure A sham exposure was conducted.
Additional information magnetic force lines were parallel to the horizontal component of the local geomagnetic field
パラメータ
測定量 種別 Method Mass 備考
磁束密度 1 mT spatial average 測定値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The motor coordination of mice that were neonatally exposed to an extremely low frequency magnetic field was significantly impaired compared to the control group. However, no significant difference was observed between the prenatally exposed group and the control group.

研究の種別:

研究助成

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