研究のタイプ: 医学/生物学の研究 (observational study)

[Hsp70は携帯電話の高頻度使用者での独立したストレスマーカである] med./bio.

Hsp70 is an independent stress marker among frequent users of mobile phones.

掲載誌: J Environ Pathol Toxicol Oncol 2014; 33 (4): 339-347

この研究は、高頻度の携帯電話使用者(FUMPs)において、血清中の熱ショックタンパク質HSP70およびC反応性タンパク質(CRP)、hsp70遺伝子発現レベルを測定した。IT関連従業員からの120人をFUMPs群とし、非IT従業員からの102人を対照群(使用が頻回でない使用者:IFUMPs)とした。その結果、IFUMPs群に比べ、FUMPs群では血清中のHSP70およびCRPの濃度が有意に高かった;同様にhsp70遺伝子発現レベルも高かった、と報告している。

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研究目的(著者による)

The effects of frequent mobile phone use on stress marker levels in the blood should be investigated.

詳細情報

A total of 120 frequent users of mobile phones (111 men, 9 women; exposure group) and 102 infrequent users of mobile phones (77 men, 25 women; control group) volunteered for this study. Subjects of the exposure group were employees of an IT company with exposure to mobile base stations and a mobile phone use of more than 5 hours/day. Subjects in the control group had a maximum mobile phone usage of 30 minutes/day.
For parts of the analysis, the exposure group was further divided into subgroups, according to the total number of years of mobile phone usage: 1) mobile phone usage for 1-5 years (n=50), 2) 6-10 years (n=65) and 3) for >10 years (n=5).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1:
ばく露時間: daily mobile phone > 5 hours for 1-5 years
-
ばく露2:
ばく露時間: daily mobile phone > 5 hours for 6-10 years
-
ばく露3:
ばく露時間: daily mobile phone > 5 hours for > 10 years
-

General information

In the method section, the authors write: "The make and specific absorption rate of the mobile phones were noted in a questionnaire." However, these data are not presented or mentioned in the further course of the study.

ばく露1

主たる特性
周波数
タイプ
  • electromagnetic field
ばく露時間 daily mobile phone > 5 hours for 1-5 years
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
ばく露装置の詳細 subjects working in an IT sector company and beeing exposed to mobile base stations
パラメータ

No parameters are specified for this exposure.

ばく露2

主たる特性
周波数
タイプ
  • electromagnetic field
ばく露時間 daily mobile phone > 5 hours for 6-10 years
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ

No parameters are specified for this exposure.

ばく露3

主たる特性
周波数
タイプ
  • electromagnetic field
ばく露時間 daily mobile phone > 5 hours for > 10 years
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ

No parameters are specified for this exposure.

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The serum levels of C-reactive protein and Hsp70 as well as the gene expression of hsp70 were significantly increased in the exposure group compared to the control group.
The authors conclude that frequent mobile phone use might elevate levels of the stress markers C-reactive protein and Hsp70 in the blood.

研究の種別:

研究助成

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