研究のタイプ: 医学/生物学の研究 (experimental study)

[振幅変調マイクロ波刺激に対するニューロンの反応] med./bio.

Responses of neurons to an amplitude modulated microwave stimulus

掲載誌: Neurosci Lett 2002; 333 (3): 175-178

この研究は、GSM携帯電話の信号と同様のパルス無線周波信号(搬送波900MHz、217Hzで変調)がキンカチョウの脳の神経細胞に与える影響を調べた(34羽を麻酔下で実験;全部で脳の133箇所の脳活動を測定した)。その結果、ばく露により、脳の細胞の半分以上において、神経細胞活動の変化が生じた;ばく露に反応した細胞の部分(76%)は、発火率を平均3.5倍上昇させた;その他の反応細胞では、自発的活動の発生率低下が見られた、と報告している。

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研究目的(著者による)

To investigate the effects of a pulsed radio frequency signal similar to the signal produced by global system for mobile communication (GSM) telephones on neurons of the avian brain.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 10 min
ばく露2: 900 MHz
Modulation type: CW
ばく露時間: continuous for 10 min

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for 10 min
Modulation
Modulation type pulsed
Duty cycle 12.5 %
Repetition frequency 217 Hz
Pulse type rectangular
ばく露装置
ばく露の発生源/構造
チャンバの詳細 A tuned resonant RF cavity of 3λ length was used (23.5 cm diameter, 100.5 cm long) made of perforated metal producing a standing wave and fitted with two tuned RF stubs each 16.5 cm (λ/2) from opposite ends and thus 2λ from each other: one for emitting the signal and one for monitoring the frequency and power of the signal being synchronized in phase and intensity to the emitted signal.
ばく露装置の詳細 The anesthetized bird was mounted in a non-conducting plastic holder and placed inside the cavity such that its head was at the center exactly 1λ from the emitting stub and the demodulating stub. Consequently, the signal the bird's head received was exactly the signal at both of those locations. The amplified RF signal was switched between a matched load and the cable to the waveguide chamber by a single-pole, double-throw RF switch controlled by a digital signal from the computer program.
Additional information To record from neurons in the brain of the bird, a glass micro-electrode of 1-2 µm tip diameter was inserted through a small hole (4 mm) in the skull, and a silver reference electrode was inserted beneath the skin along the back of the head. Arranging the electrodes along the long axis of the cavity prevented them from acting as a loop antenna and electrically stimulating the cells.
パラメータ
測定量 種別 Method Mass 備考
電力密度 0.1 mW/cm² peak 測定値 - up to 0.5 mW/cm²
SAR 0.05 W/kg mean 計算値 - -

ばく露2

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for 10 min
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
電力密度 0.1 mW/cm² peak 測定値 - up to 0.5 mW/cm²

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中

研究の主なアウトカム(著者による)

The stimulation resulted in changes in the amount of neural activity by more than half of the brain cells. Most (76%) of the responding cells increased their rates of firing. The other cells exhibited a decrease in their rates of spontaneous activity.

研究の種別:

研究助成

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