Study type: Therapeutical study (experimental study)

Use of a pulsed electromagnetic field for treatment of post-operative pain in dogs: a pilot study med./bio.

Published in: Vet Anaesth Analg 2002; 29 (1): 43-48

Aim of study (acc. to author)

This in vivo study was performed to determine whether exposure to pulsed electromagnetic field reduces post-operative (ablation of ovaries and uterus) pain in dogs and whether it interacts with post-operative morphine analgesia.

Background/further details

16 healthy dogs weighting 10-32 kg and aged 3-36 months were examined within 6 hours post-operative at 8 different time points. Four groups were performed: 1.) control group (NaCl administration), 2.) post-operative pulsed electromagnetic field exposure (NaCl administration), 3.) post-operative morphine application and 4.) post-operative morphine application plus pulsed electromagnetic field exposure.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 500 mHz
Modulation type: pulsed
Exposure duration: intermittent, 20 min field on/20 min field off for 6 h
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Exposure 1

Main characteristics
Frequency 500 mHz
Type
Waveform
Exposure duration intermittent, 20 min field on/20 min field off for 6 h
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Setup The magnetic field unit was attached to the outside of the cage.
Additional info Control and morphine controlled dogs were handled the same way during the recovery period only the magnet field unit was non functional.
Parameters

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • during exposure

Main outcome of study (acc. to author)

Significant differences in mean arterial blood pressure occurred at 5 hours in groups 3 and 4 (mean arterial blood pressure in group 3/4 < group 2), and at 6 hours in group 4 (mean arterial blood pressure in group 4 < group 1/2) compared to control group. At 30 minutes the total pain score for group 4 was significantly less than for control group, but not significantly different from group 2 or 3.
Although no clear benefit of electromagnetic therapy was seen, the results suggest that pulsed electromagnetic field may augment morphine analgesia post-operative in dogs.

Study character:

Study funded by

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