Study type:
Medical/biological study
(experimental study)
Frequency dependence of the cardiac threshold to alternating current between 10 Hz and 160 Hz
med./bio.
By:
Malkin RA, de Jongh Curry A
Published in: Med Biol Eng Comput 2003; 41 (6): 640645
Aim of study (acc. to author)
Background/further details
Endpoint
Exposure
Exposure
Parameters
Exposure 1:
10–160 Hz
Exposure duration:
5 s
guinea pigs: I = 25 µA  3000 µA in steps of 25 µA, 50 µA or 100 µA
dogs: I = 20 µA  1000 µA in steps of 20 µA, 50 µA or 100 µA
Exposure 2:
10–160 Hz
Exposure duration:
5 s
guinea pigs: I = 25 µA  3000 µA in steps of 25 µA, 50 µA or 100 µA
dogs: I = 20 µA  1000 µA in steps of 20 µA, 50 µA or 100 µA
Exposure 3:
10–160 Hz
Exposure duration:
5 s
guinea pigs: I = 25 µA  3000 µA in steps of 25 µA, 50 µA or 100 µA
dogs: I = 20 µA  1000 µA in steps of 20 µA, 50 µA or 100 µA
Frequency
10–160 Hz
Type
Waveform
Exposure duration
5 s
Measurand
Value
Type
Method
Mass
Remarks
cf. remarks




guinea pigs: I = 25 µA  3000 µA in steps of 25 µA, 50 µA or 100 µA
cf. remarks




dogs: I = 20 µA  1000 µA in steps of 20 µA, 50 µA or 100 µA
Frequency
10–160 Hz
Type
Waveform
Exposure duration
5 s
Measurand
Value
Type
Method
Mass
Remarks
cf. remarks




guinea pigs: I = 25 µA  3000 µA in steps of 25 µA, 50 µA or 100 µA
cf. remarks




dogs: I = 20 µA  1000 µA in steps of 20 µA, 50 µA or 100 µA
Frequency
10–160 Hz
Type
Waveform
Exposure duration
5 s
Modulation type
pulsed
Pulse width
1 ms
Measurand
Value
Type
Method
Mass
Remarks
cf. remarks




guinea pigs: I = 25 µA  3000 µA in steps of 25 µA, 50 µA or 100 µA
cf. remarks




dogs: I = 20 µA  1000 µA in steps of 20 µA, 50 µA or 100 µA
Extended view
Compact view
Methods
Endpoint/measurement parameters/methodology
Investigated system:
Investigated organ system:
Time of investigation:
before exposure
during exposure
Main outcome of study (acc. to author)
Study funded by
National Institutes of Health (NIH), Maryland, USA
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