Study type: Epidemiological study (observational study)

Risk factors for leukemia in Thailand. epidem.

Published in: Ann Hematol 2009; 88 (11): 1079-1088

Aim of study (acc. to author)

A case-control study was conducted in Thailand to investigate the contribution of cellular telephone use and other factors to the etiology of leukemia.

Further details

High risk among cellular telephone users was denoted by the presence of at least one of the three following factors: ≥ 75 % of time initiating calls, ≥ 75 % of time extending antennas, or wearing metal glasses at least some of time.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 no cellular telephone use
Group 2 cellular telephone use
Group 3 cellular telephone use: low risk
Group 4 cellular telephone use: high risk
Group 5 service provider: GSM
Group 6 service provider: other
Group 7 GSM exclusive use
Group 8 GSM exclusive use: low risk
Group 9 GSM exclusive use: high risk
Group 10 use of hair dryers
Group 11 use of computers
Group 12 use of cordless telephones
Group 13 use of microwave ovens
Group 14 use of other electric appliances
Group 15 live near powerlines
Group 16 work with or near powerlines

Population

Case group

Control group

Study size

Cases Controls
Eligible 170 756
Participants 170 756
Other:

87 cases with AML, 40 with ALL, 44 with CML, and 1 with unclassidied acute leukemia

Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

Overall, there was no clear association with cellular telephone use and leukemia. There was a suggestion that risk may be increased for those with certain usage practices (group 4) and those who used GSM service (group 5). There was no significant association with the use of household appliances or living near powerlines. Acute and chronic myeloid leukemia were significantly associated with working with or near powerlines, but these results were based on low numbers.

Limitations (acc. to author)

The duration of cellular telephone use was relatively short (median 24 - 26 months). Data of the intensity and duration of occupational exposure to power lines were not available.

Study funded by

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