Due to a lack of financial resources, we unfortunately have to suspend the import of any new radio frequency and mobile phone-related articles as of now (November 27, 2017). We apologize for this inconvenience and will keep you informed.
Home
Epidemiological study

Interactions between occupational exposure to extremely low frequency magnetic fields and chemicals for brain tumour risk in the INTEROCC study.

Published in: Occup Environ Med 2017; 74 (11): 802-809

Aim of study (acc. to author)

Possible interactions between occupational exposure to extremely low frequency magnetic fields and chemicals for brain tumor risk were investigated in a 7-country population-based case-control study (INTEROCC study).

Further details

Occupational exposure to extremely low frequency magnetic fields as well as to 29 different metals, solvents or other chemical agents was assessed by particular job exposure matrices.

Endpoint/type of risk estimation

Type of risk estimation:
  • incidence

Exposure

Assessment

Exposure groups

Reference group 1 low magnetic field strength: < 50th percentile (< 0.46 µT-years) and never exposure to 1 out of 29 chemicals
Group 2 low magnetic field strength: < 50th percentile (< 0.46 µT-years) and ever exposure to 1 out of 29 chemicals
Group 3 high magnetic field strength: ≥ 50th percentile (≥ 0.46 µT-years) and never exposure to 1 out of 29 chemicals
Group 4 high magnetic field strength: ≥ 50th percentile (≥ 0.46 µT-years) and ever exposure to 1 out of 29 chemicals

Population

  • Group:
    • men
    • women
  • Age: 30–59 years
  • Observation period: 2000 - 2004
  • Study location: Australia, Canada, France, Germany, Israel, New Zealand and UK

Case group

Control group

  • Selection:
    • population-based
  • Matching:
    • sex
    • 5-year age group

Study size

Cases Controls
Total 5,399 11,112
Participants 3,978 5,601
Participation rate 74 % 50 %
Evaluable 3,761 5,404
Other: 1939 glioma cases and 1822 meningioma cases
Statistical analysis method:
  • conditional logistic regression
  • additive and multiplicative interaction models, sensitity analyses
( adjustment:
  • 5-year age group
  • sex
  • education
  • country
)

Conclusion (acc. to author)

There was no clear evidence for interactions between occupational exposure to extremely low frequency magnetic fields and any of the chemical exposures (including metals, solvents and other chemical agents) assessed for either glioma or meningioma risk. In sensitivity analyses, results were similar according to different exposure time windows, to categorization of exposure or in exposed-only analyses.
The authors concluded that there was no clear evidence for interactions between occupational exposure to extremely low frequency magnetic fields and chemical exposures in relation to glioma or meningioma risk observed.

Study funded by

  • National Health and Medical Research Council (NHMRC), Australia
  • Department of Health, UK
  • Health and Safety Executive, UK
  • Deutsches Mobilfunk Forschungsprogramm (DMF; German Mobile Phone Research Programme) at Federal Office for Radiation Protection (BfS)
  • MAIFOR Program (Mainzer Forschungsförderungsprogramm) of the University of Mainz, Germany
  • Bouygues Telecom, France
  • Cancer Society of New Zealand
  • GSM Association, UK/Ireland
  • Mobile Manufacturers Forum (MMF), Belgium
  • Ministerium für Umwelt und Verkehr, Baden-Württemberg (Ministry for the Environment and Traffic of the state of Baden-Württemberg), Germany
  • National Institutes of Health (NIH), Maryland, USA
  • International Union against Cancer (UICC; Union Internationale Contre le Cancer), Switzerland
  • Mobile Telecommunications and Health Research (MTHR), UK
  • Canadian Institutes of Health Research (CIHR)
  • 3
  • O2
  • Orange
  • T-Mobile
  • Vodafone
  • Fonds de la recherche en santé du Québec (FRSQ), Canada
  • Quality of Life and Management of Living Resources program of European Union
  • Association pour la Recherche sur le Cancer (ARC), France
  • Natural Sciences and Engineering Research Council of Canada (NSERC)
  • Canada Research Chairs (Chaires de Recherche du Canada), Ottawa, Ontario, Canada
  • Canadian Wireless Telecommunications Association (CWTA; Association canadienne des télécommunications sans fil (ACTS)), Canada
  • Guzzo Environment-Cancer Chair (University of Montréal) in partnership with Cancer Research Society (CRS) undertaken by the Environment-Cancer Fund, Canada
  • Hawkes Bay Medical Research Foundation (HBMR), New Zealand
  • SFR, France
  • University of Sydney, Australia
  • Waikato Medical Research Foundation (WMRF), New Zealand
  • Wellington Medical Research Foundation (WMRF), New Zealand
  • Government of Canada
  • AFSSET (L'Agence française de sécurité sanitaire de l'environnement et du travail) France
  • Cancer Council NSW, Australia
  • Cancer Council Victoria, Australia
  • Ministerium für Klimaschutz, Umwelt, Landwirtschaft, Natur- und Verbraucherschutz Nordrhein-Westfalen (Ministry for Climate Protection, Environment, Agriculture, Conservation and Consumer Protection of the state of North Rhine-Westphalia), Germany

Related articles

  • Navas-Acien A et al. (2002): Interactive effect of chemical substances and occupational electromagnetic field exposure on the risk of gliomas and meningiomas in Swedish men.