Study type: Medical/biological study (experimental study)

Ultrawide-band electromagnetic pulses induced hypotension in rats. med./bio.

Published in: Physiol Behav 1999; 67 (3): 753-761

Aim of study (acc. to author)

Functional indices of the cardiovascular system (heart rate, systolic, mean, and diastolic pressures) were selected to represent biological endpoints that may be susceptible to the ultrawide-band radiation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 0.09–2.78 GHz
Modulation type: pulsed
Exposure duration: continuous for 6 min
Exposure 2: 0.1–2.5 GHz
Modulation type: pulsed
Exposure duration: continuous for 6 min

Exposure 1

Main characteristics
Frequency 0.09–2.78 GHz
Type
Waveform
Charakteristic
  • guided field
Exposure duration continuous for 6 min
Additional info medium frequency 0.5 GHz, fractional bandwidth 187%, estimated according to Foster, P. R.: Antennas and UWB signals. In: Taylor, J. D., ed. Introduction to ultra-wideband radar systems. Boca Raton, FL: CRC Press; 1995:237-248.
Modulation
Modulation type pulsed
Pulse width 1 ns
Rise time 180 ps
Repetition frequency 500 Hz
Exposure setup
Exposure source
Distance between exposed object and exposure source 72.7 cm
Chamber The tapered parallel plate GTEM cell (a flared rectangular coaxial transmission line) was 190 cm long and 92 cm high at the end. The lower compartment was 38.5 cm wide and 16.5 cm high at the rat's location.
Setup Rats were placed in an exposure holder made from an acrylic tube (6.5 cm i.d., 3.2 mm wall thickness, 28 cm length) with ventilation slots and polyethylene endcaps. The major axis of the animal was placed in parallel with the magnetic vector at 72.7 cm from the source end of the GTEM cell. The animal was isolated from the ground plane by placing the exposure holder on an acrylic stand of 4.2 cm height.
Sham exposure A sham exposure was conducted.
Additional info During sham exposure, all UWB conditions were maintained except for the trigger pulses to cause the spark.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 93 kV/m peak value measured - ± 5 kV/m
power density 1.15 mW/cm² mean unspecified - -
SAR 70 mW/kg average over mass unspecified whole body -

Exposure 2

Main characteristics
Frequency 0.1–2.5 GHz
Type
Waveform
Charakteristic
  • guided field
Exposure duration continuous for 6 min
Additional info medium frequency 0.49 GHz, fractional bandwidth 185%
Modulation
Modulation type pulsed
Pulse width 1.03 ns
Rise time 200 ps
Repetition frequency 1,000 Hz
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 84.6 kV/m peak value measured - ± 4 kV/m
power density 1.96 mW/cm² mean unspecified - -
SAR 121 mW/kg average over mass unspecified whole body -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Significant decrease in arterial blood pressure (hypotension) was found. In contrast, heart rate was not altered by these exposures. The ultrawide-band radiation-induced hypotension was a robust, consistent, and persistent effect.

Study character:

Study funded by

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