Study type: Medical/biological study (experimental study)

The effects of microwave radiation on microtubules and axonal transport. med./bio.

Published in: Radiat Res 1977; 70 (1): 212-223

Aim of study (acc. to author)

To study the effect of 3.1 GHz pulsed microwave radiation on the chemical and functional properties of microtubules in vitro: 1. Colchicine-binding properties of microwave-irradiated brain extracts, 2. the assembly of microtubules in brain extracts during microwave irradiation, 3. the effect of microwave irradiation on the protein transport in nerve axons in vitro.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 3.1 GHz
Modulation type: pulsed
Exposure duration: 300, 480, 600 and 900 s
Exposure 2: 3.1 GHz
Modulation type: pulsed
Exposure duration: 10 min
Exposure 3: 3.1 GHz
Modulation type: pulsed
Exposure duration: continuous for 24 h

General information

Colchicine binding; in vivo studies

Exposure 1

Main characteristics
Frequency 3.1 GHz
Exposure duration 300, 480, 600 and 900 s
Modulation
Modulation type pulsed
Pulse width 1.4 µs
Repetition frequency 200 Hz
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.4 m
Setup Samples kept in 2 PTFE containers with inner dimensions 24 x 21 x 3 mm, one was used for irradiation and the other served as control, which was placed 1 m in front of a wall lined with microwave absorbing material.
Parameters
Measurand Value Type Method Mass Remarks
power density 240 W/m² minimum measured - 520 W/m² max value

Exposure 2

Main characteristics
Frequency 3.1 GHz
Exposure duration 10 min
Modulation
Modulation type pulsed
Pulse width 1.4 µs
Repetition frequency 200 Hz
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
power density 900 W/m² mean measured - -

Exposure 3

Main characteristics
Frequency 3.1 GHz
Exposure duration continuous for 24 h
Modulation
Modulation type pulsed
Pulse width 1.4 µs
Repetition frequency 100 Hz
Exposure setup
Exposure source
Additional info Rabbit vagus nerves and nodose ganglia in 2 blocks, containing five two compartment chambers were either irradiated or served as control.
Parameters
Measurand Value Type Method Mass Remarks
power density 300 W/m² unspecified measured - -

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results did not reveal any noticeable effect of microwave irradiation on microtubules or axonal transport.

Study character:

Study funded by