phosphatidylinositol 4,5-diphosphate

Synonyms:
  • PIP2
German: Phosphatidylinositol-4,5-bisphosphat
Japanese: ホスファチジルイノシトール 4,5-二リン酸

Biochemistry. Phospholipid of the cell membranes involved in the signal transduction system resulting in increase of intracellular calcium. It is the major substrate for receptor-stimulated phosphoinositidase C, with the breakdown to the second messengers inositol 1,4,5-triphosphate and diacylglycerol.

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