• c-Myc
German: Myc
Japanese: Myc

Molecular genetics. 1. c-Myc proteins are cellular DNA-binding proteins. They are produced by the myc genes in response to cell stimuli. The transcription factor c-Myc is involved in cell growth and differentiation. Overexpression of Myc proteins leads to elevated proliferation that can cause tumorigenesis.

2. Proto-oncogene myc is one of the immediate early genes that are expressed in absence of de novo protein synthesis.

Notation: myc (italics) refers to the gene, Myc (first letter capitalized) to the protein. Prefix c- denotes the cellular form compared to v-, the viral form.

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