DNA mismatch repair

  • mismatch repair
German: DNA-Mismatch-Reparatur
Japanese: DNAミスマッチ修復

Molecular genetics. A DNA repair process that corrects mismatches between nucleic bases in the parent and daughter strands of DNA that make hydrogen bonding impossible. Enzymes remove the mismatched nucleic base in the newly synthesized strand and replace it with the correct one.
Mismatch repair plays a role in the correction of mismatches that occur during DNA replication or arise as a result of nucleic base damage due to normal metabolic stress. Mismatch repair was originally described in bacteria and later on also found in humans and animals.

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