Medical/biological study (experimental study)

Synergistic effect of microwave heating and hydrogen peroxide on inactivation of microorganisms med./bio.

By: Kuchma T

Published in: J Microw Power Electromagn Energy 1998; 33 (2): 77-87

To study the combined effects of microwave heating with hydrogen peroxide simultaneously on cellular (bacterial survival) and molecular levels.

Exposure	Parameters
Exposure 1: 2.375 GHz Exposure duration: until temperatures of 40°C , 50°C and 60°C	-

Frequency	2.375 GHz
Charakteristic	guided field
Exposure duration	until temperatures of 40°C , 50°C and 60°C

Exposure source	rectangular waveguide
Setup	Portions of cell suspension were added to the cylindrical test tubes (18 mm diameter) with cone shape ends
Additional info	The sample containers were located in the centre of the standard rectangular waveguide parallel to the electric field

No parameters are specified for this exposure.

Absorbed power density was 25,2 W/cm³ for time periods 3, 5 and 7 seconds

Exposed system:

Investigated system:

Time of investigation:

The synergistic effect of microwave heating and low concentrations of hydrogen peroxide reached a maximum when the cells were exposed to microwave heating to 50°C and 0.08 % hydrogen peroxide simultaneously. Both maxima of cell destruction and DNA injuries have been achieved by successive exposure (microwaves + 10 min hydrogen peroxide) to 60°C and 0.08% hydrogen peroxide.

Study character:

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