Study type: Medical/biological study (experimental study)

Electromagnetic waves of 900 MHz in acute pentylenetetrazole model in ontogenesis in mice. med./bio.

Published in: Neurol Sci 2003; 24 (3): 111-116

Aim of study (acc. to author)

To measure the effects of mobile phones on pentylenetetrazole (PTZ)-induced seizures in both prepubertal and adult mice. PTZ is known to impair GABA-mediated inhibition. Mice were exposed before an injection of PTZ.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: continuous for 2 h or 20 h

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 2 h or 20 h
Additional info Erdinc OO, Baykul MC, Ozdemir AO, Ozkan S, Ozdemir G (1999) Effects of electromagnetic waves of 900 MHz in the pentylenetetrazol seizure model in mice. Epilepsia 40 S7:38 (abstract)
Exposure setup
Exposure source
Chamber basket-box
Sham exposure A sham exposure was conducted.
Additional info After the exposure or sham exposure the mice were injected i.p. with 60 mg/kg of pentylenetetrazole (PTZ).
Parameters
Measurand Value Type Method Mass Remarks
power 0.25 mW - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

A statistically significant difference was found between the latency measurements within 20 h for prepubertal mice in stages 1 and 2 (stage 1: facial twitching, stage 2: mild myoclonic movements in the extremities). In these animals, latency was reduced. Between the other groups, no differences were revealed.The effects on prepubertal mice of long-term 900 MHz electromagnetic waves in a PTZ model may be an indication of possible problems in developing brains.

Study character:

Study funded by

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