Study type: Review (medical/biological study)

Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: Gene Expression in Response to Static Magnetism in Cultured Rat Hippocampal Neurons review

Published in: J Pharmacol Sci 2005; 98 (3): 219-224

Aim of study (acc. to author)

The article deals with possible expression of particular transcription factors responsive to static magnetic fields as a guidepost for possible functional alterations induced by magnetism in the brain. Furthermore, an aspect on the search for genes expressed in response to sustained magnetism in cultured rat hippocampal neurons using a differential display technique is also discussed.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: continuous for 15 min

Exposure 1

Main characteristics
Frequency
Type
Exposure duration continuous for 15 min
Exposure setup
Exposure source
  • not specified
Additional info Control neurons were not exposed to magnetic field.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 100 mT - unspecified - -

Main outcome of study (acc. to author)

It appears that static magnetic field may modulate cellular integrity and functionality through expression of a variety of responsive genes required for gene transcription and translation, proliferation, differentiation, maturation, survival, and so on in cultured rat hippocampal neurons.

Study character:

Exposure

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