Study type: Medical/biological study (experimental study)

Nonlinear EEG activation evoked by low-strength low-frequency magnetic fields. med./bio.

Published in: Neurosci Lett 2007; 417 (2): 212-216

Aim of study (acc. to author)

This in vivo study was designed to further analyze the result of a previous study (see publication 15027) that electromagnetic field exposure evoke nonlinear magneto-sensory potentials in humans.

Background/further details

Eight clinical normal subjects (two males aged between 30 and 45 years; six females aged between 18 and 65 years) were examined. Under the hypothesis that magneto-sensory evoked potentials are nonlinear, the brain electrical responses exhibited by human subjects would be expected to differ even when the exposures were replicated. Therefore, the participants were exposed at two times separated by at least one week and results compared in this regard.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Modulation type: pulsed
Exposure duration: 2 s pulses with 5 s intervall

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Waveform
Exposure duration 2 s pulses with 5 s intervall
Modulation
Modulation type pulsed
Pulse width 2 s
Exposure setup
Exposure source
Setup field applied in the coronal plane
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 100 µT - - - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Using recurrence analysis (nonlinear analysis), magneto-sensory evoked potentials were detected in each subject in both the initial and replicate studies, with one exception. All magneto-sensory evoked potentials exhibited characteristics, indicating that they were nonlinearly related to the magnetic field stimulus.
Using time averaging (linear analysis) the magneto-sensory evoked potentials were not detected, thereby further confirming their nonlinearity.

Study character:

Study funded by

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