Microwaves of the frequencies 150.176 to 150.664 GHz correspond to frequencies of the molecular radiation and absorption spectrum of nitric oxide. One of the features of nitric oxide is the inhibition of platelet aggregation which occurs as a reaction to stress.
In this study, immobilization stress was induced by fixation of the animals in the supine posture for 3 hours. 60 male rats, 60 female estrus rats, and 60 female diestrus rats were investigated. The animals were divided into following groups: 1) control, 2) stressed animals, 3) stressed animals exposed to microwaves for 15 min, and 4) stressed animals exposed to microwaves for 30 min.
Exposure duration: continuous for 15 min. or 30 min.
Functional activity in platelets was increased in rats of both sexes in a state of acute immobilization stress. Exposure of stressed animals to microwaves in the nitric oxide frequency band restored the impaired platelet aggregation activity. Female rats were more sensitive and gained complete recovery of platelet aggregation after 15 min exposure whereas in male rats complete recovery was observed only after 30 min exposure. 30 min exposure led in stressed diestrus rats to complete recovery whereas a reduced functional activity of platelets was observed in stressed estrus rats.
The authors concluded that female rats were more sensitive to the microwave exposure than male rats. Furthermore, a relationship between exposure and phase of estrous cycle was found: estrus female rats exhibited maximum sensitivity to microwave exposure.