Study type: Medical/biological study (experimental study)

Intracellular Ca(2+) levels in rat ventricle cells exposed to extremely low frequency magnetic field. med./bio.

Published in: Electromagn Biol Med 2011; 30 (1): 14-20

Aim of study (acc. to author)

To study the effects of a magnetic field on intracellular Ca2+ levels in cardiac ventricle cells of rats.

Background/further details

45 rats were divided into three groups: control group, sham exposure group and exposure group (each group n=15).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 3 h/day on 14 days

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 3 h/day on 14 days
Exposure setup
Exposure source
Setup two pairs of Helmholtz coils with a diameter of 25 cm, positioned as a vertical and a horizontal pair with a distance of 25 cm each; coils made of 300 turns of copper wire with a diameter of 0.85 mm; animals exposed in 17 cm x 17 cm x 25 cm metacrylate boxes
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.25 mT spatial average measured - +/- 0.01 mT

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Increased heterogeneous Ca2+ accumulations were found in myofibril regions of the exposure group compared with the control roups. The data showed that intracellular Ca2+ accumulation in cardiac ventricles can increase in rats exposed to extremely low frequency magnetic fields.

Study character:

Study funded by

Related articles