Study type: Epidemiological study (observational study)

Case-control study of paternal occupation and childhood leukaemia in Great Britain, 1962-2006. epidem.

Published in: Br J Cancer 2012; 107 (9): 1652-1659

Aim of study (acc. to author)

A case-control study was conducted in the Great Britain to investigate the possible association between paternal occupation and the risk for childhood leukemia.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Population

Case group

Control group

Study size

Cases Controls
Eligible 17,793 16,764
Evaluable 16,764 16,764
Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

No statistically significant increased risks for total childhood leukemia, lymphatic leukemia, and acute myeloid leukemia were observed in association with paternal exposure to electromagnetic fields. However, the risk of other types of leukemia was significantly increased by paternal exposure to electromagnetic fields (adjusted OR 1.60; CI 1.11-2.33 based on 119 case-control pairs).
The authors concluded that the results show some support for a positive association between childhood leukemia risk and paternal occupation involving social contact. Additionally, the study provided additional evidence for higher occupational social class being a risk factor for childhood leukemia.

Study funded by

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