Study type: Epidemiological study (observational study)

Associations of parental occupational exposure to extremely low-frequency magnetic fields with childhood leukemia risk. epidem.

Published in: Leuk Lymphoma 2016; 57 (12): 2855-2862

Aim of study (acc. to author)

The association of parental occupational exposure to extremely low-frequency magnetic fields with childhood leukemia risk was investigated in a meta-analysis.

Further details

Following 12 studies were included: Shu et al. (1988), Infante-Rivard et al. (1991), Sorahan et al. (1999), Smulevich et al. (1999), Feychting et al. (2000), Infante-Rivard et al. (2003), McKinney et al. (2003), Ali et al. (2004), Pearce et al. (2007), Hug et al. (2010), Reid et al. (2011) and Keegan et al. (2012).

Endpoint/type of risk estimation

Type of risk estimation:

Exposure

Population

Statistical analysis method:

Conclusion (acc. to author)

The overall results showed that neither maternal nor paternal occupational exposure to extremely low-frequency magnetic fields was associated with childhood leukemia risk (OR 1.01, CI 0.88-1.16).
In subgroup analysies of the paternal occupational exposure, significant association was found when pooling studies with small number of cases (OR 1.96, CI, 1.03-3.74) or with lower quality score (OR 1.52, CI, 1.07-2.15). However, this association was not confirmed when pooling studies with large number of cases or high quality score.
The authors conclude that the data indicate no association between parental occupational exposure to extremely low-frequency magnetic fields and childhood leukemia risk. The elevated odds ratios under certain subgroup analysis is likely due to chance.

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