Study type: Medical/biological study (experimental study)

Effect on the immune system of mice exposed chronically to 50 Hz amplitude-modulated 2.45 GHz microwaves. med./bio.

Published in: Bioelectromagnetics 1996; 17 (3): 246-248

Aim of study (acc. to author)

To study the effect of continuous wave or amplitude modulated microwave irradiation on the immune response.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: AM
Exposure duration: 3 h/day on 6 consecutive days
  • SAR: 0.14 W/kg average over mass (unspecified) (+/- 0.02 W/kg)
  • power density: 0.1 mW/cm² average over time (at the center of the cage)
Exposure 2: 2.45 GHz
Modulation type: CW
Exposure duration: 3 h/day on 6 consecutive days
  • SAR: 0.14 W/kg average over mass (unspecified) (+/- 0.02 W/kg)
  • power density: 0.1 mW/cm² average over time (at the center of the cage)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
  • rectangular
Exposure duration 3 h/day on 6 consecutive days
Modulation
Modulation type AM
Modulation frequency 50 Hz
Exposure setup
Exposure source
Setup animals in a circular cage in a 2.55 m X 1.8 m X 2.9 m anechoic chamber
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.14 W/kg average over mass - unspecified +/- 0.02 W/kg
power density 0.1 mW/cm² average over time - - at the center of the cage

Exposure 2

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration 3 h/day on 6 consecutive days
Modulation
Modulation type CW
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.14 W/kg average over mass - unspecified +/- 0.02 W/kg
power density 0.1 mW/cm² average over time - - at the center of the cage

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Continuous wave exposures induced elevations of the number of antibody-producing cells in the spleen of male mice. Amplitude modulated microwave exposure induced elevation of the spleen index and antibody-producing cell number in the spleen of male mice. No alterations were found in female mice. It is concluded that both types of irradiation conditions induced moderate elevation of antibody production only in male mice.

Study character:

Study funded by