Study type: Medical/biological study (experimental study)

No influence of acute RF exposure (GSM-900, GSM-1800, and UMTS) on mouse retinal ganglion cell responses under constant temperature conditions. med./bio.

Published in: Bioelectromagnetics 2014; 35 (1): 16-29

Aim of study (acc. to author)

To examine possible non-thermal effects of an exposure to radiofrequency electromagnetic fields on retinal ganglion cells of mice.

Background/further details

Retinae, isolated from mouse eyes, were exposed to GSM-900, GSM-1800, and universal mobile telecommunications system (UMTS) signals with different specific absorption rates of 0 (sham exposure), 0.02, 0.2, 2, and 20 W/kg. Before, during and after (up to 35 minutes) the exposure, the responses of retinal ganglion cells to light stimuli (different intensities) were recorded.
Apart from being particularly exposed during mobile phone use, the retina can also serve as a model for neuronal tissue in general.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: 30 minutes (three blocks of 10 minutes, respectively)
GSM-900
Exposure 2: 1,750 MHz
Exposure duration: 30 minutes (three blocks of 10 minutes, respectively)
GSM-1800
Exposure 3: 1,966 MHz
Exposure duration: 30 minutes (three blocks of 10 minutes, respectively)

General information

i) GSM 900 (0.02 W/kg, 0.2 W/kg, 2 W/kg, 20 W/kg) ii) GSM-1800 (0.02 W/kg, 0.2 W/kg, 2 W/kg, 20 W/kg) iii) UMTS (0.02 W/kg, 0.2 W/kg, 2 W/kg, 20 W/kg)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration 30 minutes (three blocks of 10 minutes, respectively)
Additional info GSM-900
Exposure setup
Exposure source
Chamber retina was placed into a preperation chamber and then mounted into the radiofrequency resonator, retina was continuously superfused with Ringer's solution, temperature was 35 °C (± 0.5-1 °C for GSM-900 and ± 0.5 °C for GSM-1800 and UMTS)
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.02 W/kg - measured and calculated - -
SAR 0.2 W/kg - measured and calculated - -
SAR 2 W/kg - measured and calculated - -
SAR 20 W/kg - measured and calculated - -

Exposure 2

Main characteristics
Frequency 1,750 MHz
Type
Exposure duration 30 minutes (three blocks of 10 minutes, respectively)
Additional info GSM-1800
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.02 W/kg - measured and calculated - -
SAR 0.2 W/kg - measured and calculated - -
SAR 2 W/kg - measured and calculated - -
SAR 20 W/kg - measured and calculated - -

Exposure 3

Main characteristics
Frequency 1,966 MHz
Type
Exposure duration 30 minutes (three blocks of 10 minutes, respectively)
Additional info UMTS
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.02 W/kg - measured and calculated - -
SAR 0.2 W/kg - measured and calculated - -
SAR 2 W/kg - measured and calculated - -
SAR 20 W/kg - measured and calculated - -

Reference articles

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

No significant changes between the responses to light stimuli in the sham exposed and in the exposed groups were observed.
The data indicate that exposure to radiofrequency electromagnetic fields at GSM-900, GSM-1800 and UMTS-signals has no non-thermal effect on retinal ganglion cell responses of mice.

Study character:

Study funded by

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