Study type: Medical/biological study (experimental study)

Behavioral and physiological effects of chronic 2,450-MHz microwave irradiation of the rat at 0.5 mW/cm2. med./bio.

Published in: Bioelectromagnetics 1986; 7 (1): 45-56

Aim of study (acc. to author)

To study reactivity to electric footshock, blood levels of cholinesterase and sulfhydryl groups, urinary output of 17-ketosteroids, and deficits of performance in the shuttle box during or after chronic microwave exposure of a pigmented strain of rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 630 h altogather (7 h/d, 7 d/wk)

General information

Rats were placed either in microwave or sham irradiation chamber

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration 630 h altogather (7 h/d, 7 d/wk)
Modulation
Modulation type CW
Exposure setup
Exposure source
  • monopole
Chamber Anechoic chamber/ 3.5 x 3.5 x 2.75 m
Additional info Electric field was parallel to the long axis of the cage and the rat.
Parameters
Measurand Value Type Method Mass Remarks
power density 5 W/m² mean measured - -
SAR 140 µW/g mean cf. remarks partial body 0.11 to 0.18 W/kg; determined by twin well calorimetry method

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Daily measures of body mass and food and water intake indicated no statistically significant effects of microwave irradiation. Monthly assessment of reactivity to electric footshock, levels of cholinesterase and sulfhydryl groups in blood, and 17-ketosteroids in urine revealed no reliable differences between sham-exposed and microwave-exposed animals.
After the 90 days of irradiation, rats from each group were assessed for open field behavior, shuttlebox performance, and schedule-controlled lever pressing for food pellets. Statistically significant differences between microwave-exposed and sham-exposed animals were found in shuttlebox performances and lever pressing.
Post mortem measures of mass of several organs and microscopic examination of adrenal tissue revealed no differences between the two groups of rats. In summary, the results of chronic intermittent irradiation of rats to 0.5 mW/cm² appear to be minor or of little biological significance.

Study character:

Study funded by

Replication studies

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