To investigate the microwave absorption properties of plasmid DNA molecules of homogeneous size with the surprising observation of resonant absorption by the molecules in aqueous solution. Physicochemical changes in plasmids exposed to the resonant frequency were investigated.
|Exposure duration||continuous for 20 min|
The work reports an observed power-dependent and temperature-independent effect of microwaves on isolated DNA molecules in solution. Exposure at or near the resonant frequency resulted in single- and double-strand breaks of supercoiled plasmid DNA as shown by an accompanying increase in the amount of relaxed and linear forms of the molecule, respectively.