Study type: Medical/biological study (experimental study)

No effect of a low-frequency pulsed magnetic field on the brain blood flow among mice med./bio.

By: Bellossi A, Nicol L, Dazord L
Published in: Panminerva Med 1993; 35 (1): 57-59
Download citation in RIS format

Aim of study (acc. to author)

To investigate possible alterations of brain blood flow in mice after exposure with a low frequency pulsed magnetic field.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 12 Hz
Exposure duration: continuous for 30 min
Exposure 2: 460 Hz
Exposure duration: continuous for 30 min

Exposure 1

Main characteristics
Frequency 12 Hz
Type
Waveform
Exposure duration continuous for 30 min
Modulation
Modulation type unspecified
Exposure setup
Exposure source
  • 2 applicators, 12 cm in diameter
Distance between exposed object and exposure source 0.018 m
Chamber altuglas container divided into 29 x 29 x100 mm compartment, each held a mouse
Additional info The applicators were placed on the top of the container with the center of container located 18 mm from surface of emitter disc
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 6 mT peak value measured - -

Exposure 2

Main characteristics
Frequency 460 Hz
Type
Waveform
Exposure duration continuous for 30 min
Modulation
Modulation type unspecified
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.018 m
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 6 mT peak value measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In this study radioactive Technetium (99mTc) was used as a lipophylous tracer which is capable to cross the blood brain barrier. It was injectes i.v. 0, 3, or 24 h after exposure. No differences between control and exposed animals could be found.

Study character:

Study funded by