Study type: Medical/biological study (experimental study)

Effects of continuous and pulsed 2450-MHz radiation on spontaneous lymphoblastoid transformation of human lymphocytes in vitro. med./bio.

Published in: Bioelectromagnetics 1992; 13 (4): 247-259

Aim of study (acc. to author)

To compare spontaneous lymphocyte transformation obtained by pulsed or CW microwaves and conventional heating. Its dependence on the exposure conditions was investigated.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: pulsed, CW
Exposure duration: 5 days

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration 5 days
Modulation
Modulation type pulsed, CW
Pulse width 1 µs
Repetition frequency 1 Hz
Additional info

packets/second : 100-1000

Exposure setup
Exposure source
Setup a four chamber slide sample holders placed on a polystyrene block which was placed in waveguide (10.9 cm x 5.4 cm).
Additional info waveguide placed in a conventional CO2 incubator.
Parameters
Measurand Value Type Method Mass Remarks
SAR 1 W/kg mean measured - 0.8 - 1.3 W/kg (CW exposure)
SAR 12.3 W/kg peak value measured - 9.8 - 12.3 kW/kg (PW exposure)

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

CW exposure at physiological temperatures (37°C) does not affect spontaneous lymphoblastoid transformation. Conventional and CW heating enhance lymphoblastoid transformation to the same degree under small temperature elevations (however, CW microwave heating leads to cell destruction at smaller temperature elevations than is the case for conventional heating, which might result from small temperature differences between these two exposure modalities). The most notable finding is enhancement of lymphoblastoid transformation at a non-heating level caused by pulsed wave (PW) exposure. No such enhancement was observed following CW exposure. PW and CW exposures act differently in causing transformation of human lymphocytes in vitro.

Study character:

Study funded by

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