Study type: Medical/biological study (experimental study)

Effects of microwave exposure at various power densities on mitochondrial marker enzymes in mouse brains med./bio.

By: Chiang H, Yao GD, Zhou S
Published in: J Bioelectricity 1984; 3 (3): 361-366
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Aim of study (acc. to author)

To investigate the effect of microwave exposure on the amount of two mitochondrial marker enzymes.

Background/further details

Following irradiation and decapitation brains were dissected, and tissue slices of hypothalamus and hippocampus were prepared. The enzyme amount was studied by histochemical methods.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 3 GHz
Modulation type: pulsed
Exposure duration: continuous for 3 h
Exposure 2: 2.45 GHz
Modulation type: CW
Exposure duration: continuous for 3 h

Exposure 1

Main characteristics
Frequency 3 GHz
Type
Exposure duration continuous for 3 h
Modulation
Modulation type pulsed
Pulse width 1.2 µs
Repetition frequency 935 Hz
Exposure setup
Exposure source
Setup The animals were placed individually in small Plexiglas cages with their bodies parallel to the E vector.
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 5 mW/cm² - measured - -
power density 1 mW/cm² - measured - -
power density 0.5 mW/cm² - measured - -
power density 0.3 mW/cm² - measured - -
power density 0.1 mW/cm² - measured - -
Measurement and calculation details

The incident power densities were measured with an isotropic electromagnetic radiation monitor.

Exposure 2

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration continuous for 3 h
Modulation
Modulation type CW
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 5 mW/cm² - measured - -
power density 1 mW/cm² - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

A significant decrease of enzyme amount was found for both enzymes in hippocampus and hypothalamus, respectively. This decrease was observed at power densities of 0.5 mW/cm² or higher for 3 GHz (pulsed wave) and 1 mW/cm² or higher for 2.45 GHz (CW). The results show that pulsed wave exposure decreases more effectively the studied enzyme levels than CW exposure does.

Study character:

Study funded by