Study type: Medical/biological study (experimental study)

Comparison of the effect of the continuous and pulsed 2450-MHz microwave irradiation on the level of ATP, ADP and AMP in developing rat brain med./bio.

By: Jamakosmanovic A, Jevric A, Nakash M, Dretsun M, Shore ML
Published in: Period Biol 1983; 85 (2): 199-201
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Aim of study (acc. to author)

To evaluate continuous wave and pulsed wave exposure of 2450 MHz microwave irradiation on the level of energy rich phosphate in the rat brain.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: every 24 h for 28 days
Exposure 2: 2.45 GHz
Modulation type: pulsed
Exposure duration: every 24 h for 28 days

General information

Animals were divided into four groups. The first group and the second group were exposed to continuous wave and pulsed microwave irradiation, respectively. The third group was sham exposed and the forth group was used as control.

Exposure 1

Main characteristics
Frequency 2.45 GHz
Exposure duration every 24 h for 28 days
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup Animals were placed in a plastic cage with their head against the direction of the incident wave
Parameters
Measurand Value Type Method Mass Remarks
power density 82.6 W/m² mean unspecified - -

Exposure 2

Main characteristics
Frequency 2.45 GHz
Exposure duration every 24 h for 28 days
Modulation
Modulation type pulsed
Pulse width 2 µs
Repetition frequency 100 Hz
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
power density 82.6 W/m² mean unspecified - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

When compared to the control animals, continuous wave repetitive irradiation resulted in insignificant increase of the ATP level, significant decrease of the ADP level by 48%, and significant increase of the AMP level by 23%.
When compared to the control animals, pulsed wave repetitive irradiation resulted in insignificant increase in the ATP level, significant decrease of the ADP level by 55%, and insignificant decrease of the AMP level.
When comparing the effects of continuous wave and pulsed wave microwave irradiation, the only difference was in the increase of the AMP level obtained by continuous wave exposure. A significant decrease of the ADP level was revealed by both types of microwave irradiation.

Study character:

Study funded by