Molecular genetics. 1. c-Fos proteins are cellular DNA-binding proteins. They are produced by the c-fos genes in response to cell stimuli. c-Fos protein combines with c-Jun protein to form the AP-1 transcription factor that regulates the expression of many growth-related genes.
2. Proto-oncogene c-fos is one of the immediate early genes that are expressed in absence of de novo protein synthesis.
Notation: fos (italics) refers to the gene, Fos (first letter capitalized) to the protein. Prefix c- denotes the cellular form compared to v-, the viral form.
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